Dr.GutHealth said:Glucagon receptor agonism and is not that straightforward in my experience
This is exactly right. Dr.GutHealth articulated what I have been trying to explain to my doctor for months. The Glucagon receptor agonism aspect is the most important factor.
Reading this thread on Glucagon receptor agonism hits close to home. Night shift nurse — I started at 279 lbs and felt like I would tried everything.
15 months on tirz and I am a different person. Not just the 54 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about Glucagon receptor — take the leap. It was the best health decision I have ever made. ❤️
Dr.AddMedPHL — that is really helpful context on Glucagon receptor agonism. Follow-up question: what labs did your doctor order to monitor this?
I am in a similar situation (just started) and trying to set realistic expectations.
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Shop Reference StandardsTo answer JenPlateau's question specifically:
From a clinical standpoint, Glucagon receptor agonism and is an area where we have good evidence.
The short answer: baseline labs + quarterly monitoring is the standard of care.
The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.
Bookmarked 📌 The Glucagon receptor info in this thread is essential. Coming back to this for sure.