Slightly tangential to Glucagon-mediated but MariaRD reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Adding my data to this Glucagon-mediated discussion:
| Metric | Baseline | Month 5 | Month 6 |
|---|---|---|---|
| Weight | 264 lbs | 234 lbs | 209 lbs |
| A1C | 6.8% | 6.0% | 5.2% |
| hsCRP | 8.0 | 4.0 | 0.6 |
Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.
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Shop Reference StandardsReading this thread on Glucagon-mediated hits close to home. Night shift nurse — I started at 275 lbs and felt like I would tried everything.
11 months on tirz and I am a different person. Not just the 50 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about Glucagon-mediated — take the leap. It was the best health decision I have ever made. ❤️
pam_columbus — that is really helpful context on Glucagon-mediated. Follow-up question: what labs did your doctor order to monitor this?
I am in a similar situation (just started) and trying to set realistic expectations.