Feb 25, 2026 at 7:36 AM#16
Congrats Dr.BariatricHTX!! You should be so proud of yourself. 🎉 👏
34 10RunnerRach, TrialNerd_Beth, HPLC_Greg and 31 others
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Feb 25, 2026 at 7:53 AM#17
Slightly tangential to SS-31 (Elamipretide) but newstart_MO reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
35 15Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 32 others
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Feb 25, 2026 at 8:10 AM#18
Adding my data to this SS-31 (Elamipretide) discussion:
| Metric | Baseline | Month 5 | Month 6 |
|---|---|---|---|
| Weight | 244 lbs | 244 lbs | 209 lbs |
| A1C | 6.8% | 6.0% | 5.2% |
| hsCRP | 8.0 | 4.0 | 1.0 |
Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.
35 17mike.trainer_LA, sarah_nash92, FitDadDave and 32 others
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Sigma-Aldrich — Research-Grade Standards
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Shop Reference StandardsFeb 25, 2026 at 8:27 AM#19
Reading this thread on SS-31 (Elamipretide) hits close to home. Night shift nurse — I started at 295 lbs and felt like I would tried everything.
11 months on tirz and I am a different person. Not just the 70 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about SS-31 (Elamipretide) — take the leap. It was the best health decision I have ever made. ❤️
43 19JenPlateau, SallyK_inj, CryptoCarl and 40 others
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Feb 25, 2026 at 8:44 AM#20
paige_pharma — that is really helpful context on SS-31 (Elamipretide) . Follow-up question: what labs did your doctor order to monitor this?
I am in a similar situation (just started) and trying to set realistic expectations.
26 23julia.endo, JessicaM_2024, TomFromTexas and 23 others
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