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ForumsSemaglutide (Ozempic / Wegovy)Semaglutide and lean mass: DEXA scan longitudinal data Page 6

Semaglutide and lean mass: DEXA scan longitudinal data

MikeFit_NJ Mon, Mar 2, 2026 at 8:31 PM 28 replies 916 viewsPage 6 of 6
PeptideSynthNJ
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Princeton, NJ
Mar 3, 2026 at 5:01 AM#26

Dr.NateNeph — that is really helpful context on Semaglutide and lean mass. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

50 15wanda_boise, NurseAsh_DET, BenResearch_OR and 47 others
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LipidDoc_ATL
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Apr 2024
Atlanta, GA
Mar 3, 2026 at 5:18 AM#27

Want to share my personal experience related to Semaglutide and lean mass DEXA since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 262 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 62 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Semaglutide and lean aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

41 0traveltech_sara, AttorneyGrant, DebRD_ATL and 38 others
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lori_vegas
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Aug 2024
Las Vegas, NV
Mar 3, 2026 at 5:35 AM#28

Dr.NateNeph — that is really helpful context on Semaglutide and lean mass. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

Last edited: Mar 3, 2026 at 7:35 AM
22 23oliver_london, tane_welly, Dr.PathRoch and 19 others
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emma_london
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Oct 2024
London, UK
Mar 3, 2026 at 5:52 AM#29

Want to share my personal experience related to Semaglutide and lean mass DEXA since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 279 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 69 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Semaglutide and lean aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Mar 3, 2026 at 11:52 AM
3 8JessicaM_2024, TomFromTexas, mike.trainer_LA
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anders_CPH
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Copenhagen, DK
Mar 3, 2026 at 6:09 AM#30

Just wanted to say — for anyone reading this Semaglutide and lean thread who is feeling discouraged: it gets better. The first 6 weeks are the hardest. Hang in there. 💪

Last edited: Mar 3, 2026 at 10:09 AM
50 18ChrisMacros, KetoKyle, CanadaChris and 47 others
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