🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsExercise & Body CompositionDEXA scan longitudinal data — 12 months on GLP-1 + lifting

DEXA scan longitudinal data — 12 months on GLP-1 + lifting

DataDave Fri, Mar 13, 2026 at 5:01 AM 18 replies 322 viewsPage 1 of 4
DataDave
Senior Member
1,678
8,901
Apr 2024
Washington
Online
Mar 13, 2026 at 6:26 AM#1

I hit the milestone yesterday and I promised myself when I started that I would post the full data dump for anyone who wants realistic numbers. SW: 312 lbs, CW: 211 lbs, 5'10" M/38.

Monthly weigh-ins:

MonthWeight (lbs)Monthly LossDose
Baseline3120.25 mg
1301-110.25 mg
2293-80.5 mg
3284-90.5 mg
4278-61.0 mg
5271-71.0 mg
6264-71.7 mg
7257-71.7 mg
8252-52.4 mg
9245-72.4 mg
10239-62.4 mg
11232-72.4 mg
12224-82.4 mg
13217-72.4 mg
14211-62.4 mg

DEXA Comparisons:

MetricBaseline7 Months14 Months
Body Fat %41.2%33.8%24.6%
Fat Mass (lbs)128.586.951.9
Lean Mass (lbs)183.5170.1159.1
Bone Mineral (lbs)7.27.17.0
Visceral Fat (in²)18711254

Yes, I lost lean mass. About 24 lbs of it. But I also wasn't doing any structured resistance training for the first 7 months, which was a mistake. Once I started lifting at month 8, the lean mass loss slowed considerably — lost only ~11 lbs of lean over the last 7 months vs. ~13 lbs in the first 7 despite losing roughly the same total weight.

Happy to answer any questions. This community helped me enormously when I was starting out.

35 7VendorMark, COA_Karl, MikeFit_NJ and 32 others
Reply Quote Save Share Report
RetaRick_CA
VIP Member
2,012
9,876
Jan 2024
California
Mar 13, 2026 at 6:43 AM#2

Incredible work. A few observations from someone who geeks out on this stuff:

Your visceral fat went from 187 to 54 in² — that's a 71% reduction and honestly that's where the real health transformation lives. Subcutaneous fat is cosmetic; visceral fat is what's driving metabolic disease.

The lean mass story is actually better than the headline suggests. At 312 lbs, a good portion of that "lean mass" was water retention, glycogen stores, and connective tissue that was only there to support a 312-lb frame. Functional lean mass (actual contractile muscle tissue) loss was probably closer to 12-15 lbs, which is very reasonable for 101 lbs total lost.

What does your lifting program look like now?

35 18AmyNC_wife, SkepticalSean, Dr.CardioMD and 32 others
Reply Quote Save Share Report
ricardo_MIA
Member
378
1,678
Sep 2024
Miami, FL
Mar 13, 2026 at 7:00 AM#3

This is one of the best documented journeys I've seen on here. Saving this thread.

Quick question — what was your caloric intake like? Were you tracking or just eating to appetite?

34 17CanadaChris, ZaraB_AL, JakeSmashed95 and 31 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides
MikeNYC_runner
Member
378
1,678
Jul 2024
New York, NY
Mar 13, 2026 at 7:17 AM#4

Thanks both. To answer:

Lifting: I do a basic upper/lower split 4 days per week. Nothing fancy — compound movements, progressive overload, 3x8-12 rep ranges. Bench, rows, overhead press, squats, RDLs, pull-ups (assisted at first, now bodyweight for 3x6).

Calories: I tracked loosely for the first 3 months, was averaging around 1,500-1,700/day which was a significant deficit from my estimated TDEE of ~2,800. After month 3 I stopped tracking and just ate to appetite, which naturally settled around 1,800-2,000. Currently eating about 2,100 as I'm prioritizing protein for lean mass retention. Protein target is 160g/day minimum.

33 4GenomicsKate, Dr.ObesityMed, HealthEcon_DC and 30 others
Reply Quote Save Share Report
MASHdoc_SA
Member
456
2,345
Aug 2024
San Antonio, TX
Mar 13, 2026 at 7:34 AM#5

This is incredibly motivating. I'm 3 weeks in at 289 and feeling discouraged because I've only lost 4 lbs. Seeing your month-by-month makes me realize I need to zoom out and think long term.

Last edited: Mar 13, 2026 at 10:34 AM
6 24kate.chem, DataDave, Dr.GutHealth and 3 others
Reply Quote Save Share Report

Similar Threads

Resistance training prevents 73% lean mass loss on semaglutide — RCT review11 replies
Zone 2 cardio + GLP-1: synergistic metabolic benefits — evidence18 replies
Creatine kinase elevations on GLP-1 — exercise-induced or concerning?14 replies
Body recomposition protocol: GLP-1 + progressive overload + high protein8 replies
Walking 10,000 steps/day impact on GLP-1 weight loss — pedometer study6 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register