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ForumsMASH / Liver DiseaseSemaglutide and MASH — liver fat reduction quantification Page 3

Semaglutide and MASH — liver fat reduction quantification

MASHdoc_SA Fri, Mar 13, 2026 at 3:08 PM 13 replies 146 viewsPage 3 of 3
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Mar 13, 2026 at 7:23 PM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

6 6PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 3 others
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JennaRN
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Mar 13, 2026 at 7:40 PM#12

Slightly tangential to Semaglutide and MASH but labquiet_amy reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Mar 13, 2026 at 8:40 PM
11 3PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 8 others
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chris_chi24
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Mar 13, 2026 at 7:57 PM#13
LondonLisa said:
Follow-up question: how long did you wait before increasing your dose

This is exactly right. LondonLisa articulated what I have been trying to explain to my doctor for months. The Semaglutide and MASH aspect is the most important factor.

Last edited: Mar 13, 2026 at 10:57 PM
11 16MaxMetOK, MounjBrad, nick_newbie and 8 others
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DerekSJ_a1c
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Mar 13, 2026 at 8:14 PM#14

Saving this for reference. Top-tier content.

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NicoleRaleigh
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Mar 13, 2026 at 8:31 PM#15

Adding my data to this Semaglutide and MASH discussion:

MetricBaselineMonth 3Month 8
Weight266 lbs246 lbs201 lbs
A1C7.0%5.8%5.4%
hsCRP5.02.00.8

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

21 19mike_nyc, VendorMark, COA_Karl and 18 others
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