To answer Dr.GastroMayo's question specifically:
From a clinical standpoint, Ipamorelin vs Tesamorelin is an area where we have good evidence.
The short answer: baseline labs + quarterly monitoring is the standard of care.
The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.
Adding my data to this Ipamorelin vs Tesamorelin discussion:
| Metric | Baseline | Month 3 | Month 6 |
|---|---|---|---|
| Weight | 264 lbs | 234 lbs | 219 lbs |
| A1C | 6.8% | 5.8% | 5.2% |
| hsCRP | 8.0 | 2.0 | 0.6 |
Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Ipamorelin vs Tesamorelin.
To answer pat_auckland: I started tracking everything in a spreadsheet from day 1.
Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
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Shop Reference Standardsingrid_STO — that is really helpful context on Ipamorelin vs Tesamorelin. Follow-up question: what labs did your doctor order to monitor this?
I am in a similar situation (just started) and trying to set realistic expectations.
Reading this thread on Ipamorelin vs Tesamorelin hits close to home. Dad of 2 checking in — I started at 297 lbs and felt like I would tried everything.
13 months on tirz and I am a different person. Not just the 72 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about Ipamorelin vs — take the leap. It was the best health decision I have ever made. ❤️