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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseLiver biopsy changes on semaglutide — 72-week histology data Page 3

Liver biopsy changes on semaglutide — 72-week histology data

MASHdoc_SA Wed, Mar 11, 2026 at 9:47 AM 15 replies 325 viewsPage 3 of 3
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Mar 11, 2026 at 2:02 PM#11

Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.

Thread quality is excellent — keep it up. 👍

47 20PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 44 others
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InsuranceTom
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Mar 11, 2026 at 2:19 PM#12

Slightly tangential to Liver biopsy changes on but Dr.ObesityLA reminded me — has the insurance landscape changed recently?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

32 5lucas_SP_BR, lisa_labSD, adam_van and 29 others
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bbq_ray_KC
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Mar 11, 2026 at 2:36 PM#13
mona_PHX said:
Follow-up question: what labs did your doctor order to monitor this

This is exactly right. mona_PHX articulated what I have been trying to explain to my friends for months. The Liver biopsy changes on aspect is what made the difference for me.

26 11InsuranceTom, WendyG_ATL, SaraMom3 and 23 others
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Dr.EndoIndy
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Mar 11, 2026 at 2:53 PM#14

Saving this for reference. Quality thread.

15 24DeniseRN_TPA, SandraNC_45, Dr.EndoIndy and 12 others
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Dr.PeteFamMed
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Mar 11, 2026 at 3:10 PM#15

Adding my data to this Liver biopsy changes on discussion:

MetricBaselineMonth 4Month 6
Weight244 lbs244 lbs199 lbs
A1C6.8%6.2%5.2%
hsCRP8.03.01.0

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.

49 7FranDenver, Dr.BariatricHTX, LindaRN_retired and 46 others
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