🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsSemaglutide (Ozempic / Wegovy)Semaglutide and exercise performance — VO2max and endurance data Page 4

Semaglutide and exercise performance — VO2max and endurance data

RunnerRach Thu, Jan 8, 2026 at 11:50 AM 23 replies 717 viewsPage 4 of 5
sarah_nash92
Member
712
3,123
Jun 2024
Nashville, TN
Jan 8, 2026 at 5:30 PM#16

Congrats CanadaChris!! Keep going — you're doing incredible. 🎉

5 10NauseaFreeNow, SteveThurs, B12Beth and 2 others
Reply Quote Save Share Report
FDA_TrackerJim
Senior Member
1,567
7,890
Feb 2024
Rockville, MD
Jan 8, 2026 at 5:47 PM#17

RunnerRach's experience with Semaglutide and exercise resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I had more GI issues initially. But the overall trajectory has been remarkably similar. Down 61 lbs in 6 months.

One thing I would add that RunnerRach did not mention: insurance coverage was a major hurdle.

Last edited: Jan 8, 2026 at 8:47 PM
2 8Admin, Dr.Martinez
Reply Quote Save Share Report
adam_van
Member
212
890
Nov 2024
Vancouver, CA
Jan 8, 2026 at 6:04 PM#18

Bookmarked 📌 The Semaglutide and info in this thread is essential. Coming back to this for sure.

Last edited: Jan 8, 2026 at 10:04 PM
5 15LindaRN_retired, tommy_boulder, hyun_seoul and 2 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides
Dr.GutHealth
Senior Member
1,456
7,890
Mar 2024
Minnesota
Jan 8, 2026 at 6:21 PM#19

Clinical perspective on Semaglutide and exercise performance :

I have managed over 200 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

Last edited: Jan 8, 2026 at 11:21 PM
3 9Dr.RaviCardio, jennifer_SEA, tyler_CSCS
Reply Quote Save Share Report
LeilaHI
Member
167
789
Jan 2025
Honolulu, HI
Jan 8, 2026 at 6:38 PM#20

Subscribing to this thread. Semaglutide and exercise is exactly what I've been researching. 🙏

49 0amsterdam_pete, LondonLisa, mike_nyc and 46 others
Reply Quote Save Share Report

Similar Threads

STEP 1-5 trials comprehensive summary — efficacy endpoints compiled12 replies
Oral semaglutide 50mg Phase 3 — OASIS program results16 replies
Semaglutide pharmacokinetics — half-life, Tmax, steady state modeling10 replies
Compounded semaglutide stability data — temperature and light sensitivity16 replies
0.25mg → 2.4mg titration: optimal schedule based on clinical data6 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register