Subscribing to this thread. 5-Amino-1MQ 12 month is exactly what I've been researching. 🙏

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on 5-Amino-1MQ 12 month.

To answer Dr.BariatricHTX: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Relevant to 5-Amino-1MQ 12 month update — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 245 → 115 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

AttorneyGrant said:

Thank you all for the thoughtful replies on 5-Amino-1MQ 12 month

This is exactly right. AttorneyGrant articulated what I have been trying to explain to my friends for months. The 5-Amino-1MQ 12 month aspect is what made the difference for me.

Slightly tangential to 5-Amino-1MQ 12 month but MikeKY_noInsulin reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.