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ForumsMASH / Liver DiseaseDe novo lipogenesis reduction on GLP-1 — mechanistic hepatology Page 4

De novo lipogenesis reduction on GLP-1 — mechanistic hepatology

MASHdoc_SA Fri, Mar 6, 2026 at 1:48 AM 17 replies 523 viewsPage 4 of 4
gary_naperville
Member
245
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Oct 2024
Naperville, IL
Mar 6, 2026 at 7:28 AM#16

Congrats LarryQC_SD!! Keep going — you're doing incredible. 🎉 👏

6 14SleepFixSam, PurityPaulOR, MaxMetOK and 3 others
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mia_MS2
New Member
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23
Mar 2026
Ann Arbor, MI
Mar 6, 2026 at 7:45 AM#17

Exactly this. My pharmacist said the same thing about De novo lipogenesis.

10 24FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 7 others
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amsterdam_pete
Senior Member
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6,789
Feb 2024
Netherlands
Mar 6, 2026 at 8:02 AM#18
NurseLeah_Nash said:
Especially the point about "Thank you all for the thoughtful replies

This is exactly right. NurseLeah_Nash articulated what I have been trying to explain to my friends for months. The De novo lipogenesis aspect is what made the difference for me.

4 3CanadaChris, ZaraB_AL, JakeSmashed95 and 1 other
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MounjBrad
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890
Oct 2024
Kentucky
Mar 6, 2026 at 8:19 AM#19

Same experience here with De novo lipogenesis. amsterdam_pete described it perfectly.

50 9pam_columbus, nick_SD_fit, ben_calgary and 47 others
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RunnerRach
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467
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Aug 2024
Boston, MA
Mar 6, 2026 at 8:36 AM#20

Slightly tangential to De novo lipogenesis but mia_MS2 reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

20 9tyler_CSCS, VanRx_Mike, steve_okc and 17 others
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