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ForumsOther Peptides & Research CompoundsTB-500 for the shoulder pain that started after weight loss — anyone have experience? Page 3

TB-500 for the shoulder pain that started after weight loss — anyone have experience?

sean_dublin Fri, Sep 19, 2025 at 10:09 PM 25 replies 1,558 viewsPage 3 of 5
stefan_berlin
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Oct 2024
Berlin, DE
Sep 20, 2025 at 2:24 AM#11
TirzTom said:
TB-500 for the shoulder pain that is not that straightforward in my experience

This is exactly right. TirzTom articulated what I have been trying to explain to my doctor for months. The TB-500 for the shoulder aspect is the most important factor.

48 18NeuroNate, JessicaH_TX, KevinCompounds and 45 others
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denise_HTX
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Jan 2025
Houston, TX
Sep 20, 2025 at 2:41 AM#12

Reading this thread on TB-500 for the shoulder hits close to home. Night shift nurse — I started at 299 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 74 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about TB-500 for the — take the leap. It was the best health decision I have ever made. ❤️

12 10NeuroNate, JessicaH_TX, KevinCompounds and 9 others
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LindaRN_retired
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Dec 2024
Sarasota, FL
Sep 20, 2025 at 2:58 AM#13

pete_nash — that is really helpful context on TB-500 for the shoulder. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

12 5amsterdam_pete, LondonLisa, mike_nyc and 9 others
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VanRx_Mike
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May 2024
Vancouver, CA
Sep 20, 2025 at 3:15 AM#14

To answer denise_HTX's question specifically:

From a clinical standpoint, TB-500 for the shoulder pain is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

32 16Dr.Martinez, mike_mod, SarahChen_PharmD and 29 others
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BiostatsBrad
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Jul 2024
Durham, NC
Sep 20, 2025 at 3:32 AM#15

Bookmarked 📌 The TB-500 for the info in this thread is essential. Coming back to this for sure.

23 24NicoleRaleigh, james_edin, FranDenver and 20 others
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