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ForumsOther Peptides & Research CompoundsTB-500 for the shoulder pain that started after weight loss — anyone have experience? Page 5

TB-500 for the shoulder pain that started after weight loss — anyone have experience?

sean_dublin Fri, Sep 19, 2025 at 10:09 PM 25 replies 1,558 viewsPage 5 of 5
B12Beth
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Maryland
Sep 20, 2025 at 5:14 AM#21

Congrats sean_dublin!! You should be so proud of yourself. 🎉

19 19GraceAZ_72, carl_compliance, DanielChem_CHI and 16 others
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PharmD_Rodriguez
Senior Member
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Jan 2024
Miami, FL
Sep 20, 2025 at 5:31 AM#22

Reading this thread on TB-500 for the shoulder hits close to home. Dad of 2 checking in — I started at 289 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 64 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about TB-500 for the — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Sep 20, 2025 at 10:31 AM
30 8TinaHashiRN, robert_kc, dan_philly and 27 others
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Dr.SurgeonPGH
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Pittsburgh, PA
Sep 20, 2025 at 5:48 AM#23

As a healthcare provider, I want to add some clinical context to this discussion on TB-500 for the shoulder pain that.

Building on what B12Beth said — the evidence base here is well-established. The key publications to reference are from the STEP program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
Last edited: Sep 20, 2025 at 8:48 AM
16 10PharmHunterJen, TomTeleRx, DoseLogDan and 13 others
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stefan_berlin
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Berlin, DE
Sep 20, 2025 at 6:05 AM#24

PharmD_Rodriguez — wow. This community is amazing.

7 17TirzTom, TrialTracker_MD, JennaRN and 4 others
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labquiet_amy
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Mar 2024
Cambridge, MA
Sep 20, 2025 at 6:22 AM#25

Adding my data to this TB-500 for the shoulder discussion:

MetricBaselineMonth 5Month 8
Weight242 lbs247 lbs197 lbs
A1C6.6%6.0%5.4%
hsCRP6.04.00.8

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

40 19pete_manc_UK, anna.melb_AU, mark_tokyo and 37 others
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