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ForumsSemaglutide (Ozempic / Wegovy)Oral semaglutide 50mg Phase 3 — my results so far Page 5

Oral semaglutide 50mg Phase 3 — my results so far

LindaRN_retired Sun, Nov 23, 2025 at 8:49 AM 31 replies 1,258 viewsPage 5 of 7
tony_orlando
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Nov 23, 2025 at 3:54 PM#21

SandraNC_45 — that is really helpful context on Oral semaglutide 50mg. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

14 22NauseaFreeNow, SteveThurs, B12Beth and 11 others
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LindaRN_retired
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Nov 23, 2025 at 4:11 PM#22

To answer Dr.SleepRoch's question specifically:

From a clinical standpoint, Oral semaglutide 50mg Phase 3 is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

Last edited: Nov 23, 2025 at 7:11 PM
8 22Dr.GutHealth, amsterdam_pete, LondonLisa and 5 others
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Dr.EndoIndy
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Indianapolis, IN
Nov 23, 2025 at 4:28 PM#23

Thank you tony_orlando! This is incredibly helpful. Taking this to my next appointment. 🙏

Last edited: Nov 23, 2025 at 7:28 PM
34 22marcus_mpls, DeniseRN_TPA, SandraNC_45 and 31 others
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hank_denver
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Nov 23, 2025 at 4:45 PM#24

Relevant to Oral semaglutide 50mg Phase 3 — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 215 → 115 mg/dL, hsCRP 6.0 → 0.9 mg/L. All on tirzepatide for 7 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

23 13fiona_VT, denise_HTX, raj_cambridge and 20 others
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Dr.CardioMD
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Nov 23, 2025 at 5:02 PM#25

Slightly tangential to Oral semaglutide 50mg but tony_orlando reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

8 8josh_phd_bmore, roxy_nash, tony_orlando and 5 others
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