OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on 0.25mg → 2.4mg titration.

To answer WendyG_ATL: my doctor and I discussed the options and went with brand.

Quick update: I have noticed more improvement since posting this. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Adding my data to this 0.25mg → 2.4mg titration discussion:

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

Exactly this. My pharmacist said the same thing about 0.25mg → 2.4mg.

Slightly tangential to 0.25mg → 2.4mg titration but josh_phd_bmore reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

+1 to anders_CPH. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with 0.25mg → 2.4mg titration.