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ForumsSemaglutide (Ozempic / Wegovy)0.25mg → 2.4mg titration: optimal schedule based on clinical data — looking for input Page 7

0.25mg → 2.4mg titration: optimal schedule based on clinical data — looking for input

anders_CPH Fri, Nov 7, 2025 at 2:28 AM 33 replies 1,047 viewsPage 7 of 7
Dr.PainCLE
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Cleveland, OH
Nov 7, 2025 at 12:23 PM#31

To answer Dr.LipidDallas's question specifically:

From a clinical standpoint, 0.25mg → 2.4mg titration is something I discuss with patients regularly.

The short answer: discuss this specific situation with your prescribing provider.

The longer answer involves weighing the risk-benefit ratio for your individual situation, which I am happy to elaborate on if helpful.

40 7Dr.PathRoch, mona_PHX, andrew_nyc and 37 others
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wendy_avl
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Oct 2024
Asheville, NC
Nov 7, 2025 at 12:40 PM#32

+1. This mirrors my journey exactly. The 0.25mg → 2.4mg discussion here is so valuable.

Last edited: Nov 7, 2025 at 6:40 PM
26 22DoseLogDan, SleepFixSam, PurityPaulOR and 23 others
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anders_CPH
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Copenhagen, DK
Nov 7, 2025 at 12:57 PM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on 0.25mg → 2.4mg titration.

To answer anders_CPH: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

26 14AussieAnna, BethLabQueen, ChrisMacros and 23 others
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BariatricNurseD
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Dallas, TX
Online
Nov 7, 2025 at 1:14 PM#34

Subscribing to this thread. 0.25mg → 2.4mg titration is exactly what I've been researching. 🙏

Last edited: Nov 7, 2025 at 6:14 PM
32 4tom_AK, josh_phd_bmore, roxy_nash and 29 others
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KarenAZ_mom
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Aug 2024
Scottsdale, AZ
Nov 7, 2025 at 1:31 PM#35

Slightly tangential to 0.25mg → 2.4mg titration but Dr.LipidDallas reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Nov 7, 2025 at 6:31 PM
46 12HPLC_Greg, LibrarianMeg, bri_stats and 43 others
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