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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseLiver enzymes normal for the first time in a decade Page 3

Liver enzymes normal for the first time in a decade

BethLabQueen Mon, Feb 16, 2026 at 3:17 PM 22 replies 619 viewsPage 3 of 5
Dr.PeteFamMed
Senior Member
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Jan 2024
Minneapolis, MN
Feb 16, 2026 at 7:32 PM#11
Dr.ObesityLA said:
Liver enzymes normal for the first is not that straightforward in my experience

This is exactly right. Dr.ObesityLA articulated what I have been trying to explain to my friends for months. The Liver enzymes normal for aspect is what made the difference for me.

16 22hyun_seoul, jim_asheville, matt_MKE and 13 others
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Dr.PathRoch
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2,123
Jun 2024
Rochester, MN
Feb 16, 2026 at 7:49 PM#12

Reading this thread on Liver enzymes normal for hits close to home. Dad of 2 checking in — I started at 281 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 56 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Liver enzymes normal — take the leap. It was the best health decision I have ever made. ❤️

11 16InsuranceTom, WendyG_ATL, SaraMom3 and 8 others
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patPC_UT
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Nov 2024
Park City, UT
Feb 16, 2026 at 8:06 PM#13

Dr.ObesityMed — that is really helpful context on Liver enzymes normal for. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

17 3TomFromTexas, mike.trainer_LA, sarah_nash92 and 14 others
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pat_auckland
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Jun 2024
Auckland, NZ
Feb 16, 2026 at 8:23 PM#14

To answer Dr.PathRoch's question specifically:

From a clinical standpoint, Liver enzymes normal for the is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

42 18MeganSA_TX, LarryQC_SD, wanda_boise and 39 others
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SurmountFan_IN
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May 2024
Indianapolis, IN
Feb 16, 2026 at 8:40 PM#15

Bookmarked 📌 The Liver enzymes normal info in this thread is essential. Coming back to this for sure.

2 10Dr.SurgeonPGH, rachel_ABQ
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