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ForumsMASH / Liver DiseaseLiver enzymes normal for the first time in a decade Page 5

Liver enzymes normal for the first time in a decade

BethLabQueen Mon, Feb 16, 2026 at 3:17 PM 22 replies 619 viewsPage 5 of 5
RetaRick_CA
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Feb 16, 2026 at 10:22 PM#21

Congrats BethLabQueen!! Keep going — you're doing incredible. 🎉

Last edited: Feb 16, 2026 at 11:22 PM
11 3SkepticalSean, Dr.CardioMD, EndoResFellow and 8 others
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MASHdoc_SA
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Feb 16, 2026 at 10:39 PM#22

Reading this thread on Liver enzymes normal for hits close to home. Night shift nurse — I started at 271 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 46 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Liver enzymes normal — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Feb 17, 2026 at 1:39 AM
50 22TrialTracker_MD, JennaRN, LabKate and 47 others
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julia.endo
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Feb 16, 2026 at 10:56 PM#23

As a pharmacist, I want to add some clinical context to this discussion on Liver enzymes normal for the first time.

Building on what RetaRick_CA said — the evidence base here is robust. The key publications to reference are from the SUSTAIN program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
Last edited: Feb 17, 2026 at 4:56 AM
9 21hans_munich, jason_sac26, chris_chi24 and 6 others
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steve_okc
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Feb 16, 2026 at 11:13 PM#24

MASHdoc_SA — wow. I've been looking for this exact info for weeks.

34 15CanadaChris, ZaraB_AL, JakeSmashed95 and 31 others
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dan_philly
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Philadelphia, PA
Feb 16, 2026 at 11:30 PM#25

Adding my data to this Liver enzymes normal for discussion:

MetricBaselineMonth 5Month 6
Weight264 lbs244 lbs209 lbs
A1C6.8%6.0%5.2%
hsCRP8.04.00.6

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.

1 21EndoResFellow
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