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Evidence-based GLP-1 & peptide discussion since 2023
ForumsExercise & Body CompositionThrew up at the gym on injection day - lesson learned Page 4

Threw up at the gym on injection day - lesson learned

SteveThurs Mon, Jan 26, 2026 at 4:26 PM 28 replies 982 viewsPage 4 of 6
SteveThurs
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Jan 26, 2026 at 10:06 PM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Threw up at the gym on.

To answer PharmHunterJen: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Jan 27, 2026 at 2:06 AM
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dave_SLC
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Jan 26, 2026 at 10:23 PM#17

Relevant to Threw up at the gym on — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 229 → 99 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

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kate.chem
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Jan 26, 2026 at 10:40 PM#18

100%. My provider said the same thing about Threw up at the gym.

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PharmacoVig_BOS
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Jan 26, 2026 at 10:57 PM#19

Slightly tangential to Threw up at the gym on but TrialTracker_MD reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

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mike.trainer_LA
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Jan 26, 2026 at 11:14 PM#20
SteveThurs said:
Thank you all for the thoughtful replies on Threw up at the gym on

This is exactly right. SteveThurs articulated what I have been trying to explain to my doctor for months. The Threw up at the gym on aspect is the most important factor.

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