🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsSemaglutide (Ozempic / Wegovy)Weekly injection day thread — what worked for you? Page 3

Weekly injection day thread — what worked for you?

andrew_nyc Tue, Oct 14, 2025 at 4:13 PM 42 replies 1,530 viewsPage 3 of 9
adam_van
Member
212
890
Nov 2024
Vancouver, CA
Oct 14, 2025 at 8:28 PM#11

Thank you Dr.SurgeonPGH! This is incredibly helpful. Taking this to my next appointment. 🙏

9 16FranDenver, Dr.BariatricHTX, LindaRN_retired and 6 others
Reply Quote Save Share Report
alex_tucson
Member
567
2,345
May 2024
Tucson, AZ
Oct 14, 2025 at 8:45 PM#12

Slightly tangential to Weekly injection day but andrew_nyc reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

22 4labquiet_amy, emily_PDX, Dr.SleepRoch and 19 others
Reply Quote Save Share Report
tony_orlando
Member
234
1,123
Nov 2024
Orlando, FL
Oct 14, 2025 at 9:02 PM#13

Thanks for sharing this, andrew_nyc. A few questions about your Weekly injection day experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Weekly injectio?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

37 11ZaraB_AL, JakeSmashed95, NauseaFreeNow and 34 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
andrew_nyc
Member
534
2,345
Apr 2024
New York, NY
Oct 14, 2025 at 9:19 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Weekly injection day.

To answer alex_tucson: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

24 4julia.endo, JessicaM_2024, TomFromTexas and 21 others
Reply Quote Save Share Report
Dr.PathRoch
Member
456
2,123
Jun 2024
Rochester, MN
Oct 14, 2025 at 9:36 PM#15

Adding my data to this Weekly injection day discussion:

MetricBaselineMonth 3Month 8
Weight266 lbs236 lbs201 lbs
A1C7.0%5.8%5.4%
hsCRP5.02.00.8

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

Last edited: Oct 15, 2025 at 3:36 AM
9 11Dr.MetabolicMD, RetaRick_CA, JenPlateau and 6 others
Reply Quote Save Share Report

Similar Threads

STEP 1-5 trials comprehensive summary — efficacy endpoints compiled12 replies
Oral semaglutide 50mg Phase 3 — OASIS program results16 replies
Semaglutide pharmacokinetics — half-life, Tmax, steady state modeling10 replies
Compounded semaglutide stability data — temperature and light sensitivity16 replies
0.25mg → 2.4mg titration: optimal schedule based on clinical data6 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register