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ForumsSemaglutide (Ozempic / Wegovy)Weekly injection day thread — what worked for you? Page 8

Weekly injection day thread — what worked for you?

andrew_nyc Tue, Oct 14, 2025 at 4:13 PM 42 replies 1,530 viewsPage 8 of 9
FDA_TrackerJim
Senior Member
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Oct 15, 2025 at 3:33 AM#36

Relevant to Weekly injection day thread — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 247 → 117 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

28 10Dr.Martinez, mike_mod, SarahChen_PharmD and 25 others
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B12Beth
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Oct 2024
Maryland
Oct 15, 2025 at 3:50 AM#37

Want to share my personal experience related to Weekly injection day thread since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 258 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 73 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Weekly injection day aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

39 22carl_compliance, DanielChem_CHI, marco_milano and 36 others
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SandraNC_45
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Sep 2024
Charlotte, NC
Oct 15, 2025 at 4:07 AM#38

pete_RVA — that is really helpful context on Weekly injection day. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

12 22NicoleRaleigh, james_edin, FranDenver and 9 others
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NurseAsh_DET
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1,567
Sep 2024
Detroit, MI
Oct 15, 2025 at 4:24 AM#39

Want to share my personal experience related to Weekly injection day thread since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 275 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 80 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Weekly injection day aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

35 19labquiet_amy, emily_PDX, Dr.SleepRoch and 32 others
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raj_cambridge
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Jun 2024
Cambridge, MA
Oct 15, 2025 at 4:41 AM#40

SandraNC_45 — that is really helpful context on Weekly injection day. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

15 19RickReta_CO, PharmHunterJen, TomTeleRx and 12 others
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