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ForumsSemaglutide (Ozempic / Wegovy)Reconstitution and storage guide — anyone have experience? Page 2

Reconstitution and storage guide — anyone have experience?

ingrid_STO Thu, Oct 2, 2025 at 5:10 AM 13 replies 993 viewsPage 2 of 3
zoe_NC
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Nov 2024
Charlotte, NC
Oct 2, 2025 at 8:00 AM#6

Wait I'm confused. My vial says 3mg not 5mg. Do I just use the same formula?

39 23Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 36 others
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JessicaM_2024
Member
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3,456
Mar 2024
Portland, OR
Oct 2, 2025 at 8:17 AM#7
Previously posted:
My vial says 3mg not 5mg. Do I just use the same formula?

Same exact formula, just different numbers. The universal formula is:

Volume to inject (mL) = Desired dose (mg) ÷ Concentration (mg/mL)

And concentration = Total mg in vial ÷ mL of BAC water added

So for your 3mg vial, if you add 1.5mL BAC water:

  • Concentration = 3mg / 1.5mL = 2mg/mL
  • 0.25mg dose = 0.25 / 2 = 0.125mL = 12.5 units (draw to halfway between 10 and 15)
  • 0.5mg dose = 0.5 / 2 = 0.25mL = 25 units

Or if you want easier numbers, add 1.2mL BAC water to get 2.5mg/mL, then 0.25mg = 10 units. Same as the 5mg vial example. The total number of doses per vial will be different of course (3mg total instead of 5mg).

10 10NicoleRaleigh, james_edin, FranDenver and 7 others
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LabKate
Senior Member
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11,234
Jan 2024
Oregon
Oct 2, 2025 at 8:34 AM#8

you are an absolute angel. I just did my first reconstitution and injection — 10 units, right in the belly, barely felt it. This community is the best. Thank you all so much!! 🙏🥹

Last edited: Oct 2, 2025 at 11:34 AM
3 11Dr.SleepRoch, laura_annarbor, JenMemphis
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patPC_UT
Member
212
890
Nov 2024
Park City, UT
Oct 2, 2025 at 8:51 AM#9

Pinning this thread. We get this question at least twice a week. Excellent explanations as always from our knowledgeable members. For anyone reading this in the future, we also have a reconstitution calculator in the Tools section of the wiki.

And a reminder: always verify your math before injecting. If something seems off, ask here or call your provider. It's never a dumb question when it comes to dosing.

Last edited: Oct 2, 2025 at 1:51 PM
18 13JessicaM_2024, TomFromTexas, mike.trainer_LA and 15 others
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