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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseALT normalization rates on GLP-1 — looking for input Page 3

ALT normalization rates on GLP-1 — looking for input

bbq_ray_KC Fri, Jan 30, 2026 at 9:54 AM 24 replies 793 viewsPage 3 of 5
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Jan 30, 2026 at 2:09 PM#11

Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.

Thread quality is excellent — keep it up. 👍

4 1PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 1 other
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JessicaH_TX
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Jan 30, 2026 at 2:26 PM#12

Slightly tangential to ALT normalization rates but KevinCompounds reminded me — has the insurance landscape changed recently?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Jan 30, 2026 at 6:26 PM
44 22sarah_TO, wendy_avl, jason_paloalto and 41 others
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sarah_nash92
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Jan 30, 2026 at 2:43 PM#13
Dr.RheumBOS said:
Follow-up question: what labs did your doctor order to monitor this

This is exactly right. Dr.RheumBOS articulated what I have been trying to explain to my friends for months. The ALT normalization rates aspect is what made the difference for me.

34 18ZaraB_AL, JakeSmashed95, NauseaFreeNow and 31 others
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steve_okc
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Jan 30, 2026 at 3:00 PM#14

Saving this for reference. Quality thread.

41 6CanadaChris, ZaraB_AL, JakeSmashed95 and 38 others
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hank_denver
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Jan 30, 2026 at 3:17 PM#15

Adding my data to this ALT normalization rates discussion:

MetricBaselineMonth 4Month 6
Weight256 lbs241 lbs211 lbs
A1C7.0%6.2%5.2%
hsCRP5.03.00.6

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

20 13Dr.DermMIA, fiona_VT, denise_HTX and 17 others
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