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ForumsMASH / Liver DiseaseLiver biopsy changes on semaglutide — November 2025 Page 4

Liver biopsy changes on semaglutide — November 2025

hank_denver Tue, Jan 20, 2026 at 2:54 AM 23 replies 1,081 viewsPage 4 of 5
CryptoCarl
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Jan 20, 2026 at 8:34 AM#16

Congrats greg_boulder!! You should be so proud of yourself. 🎉

Last edited: Jan 20, 2026 at 12:34 PM
6 1CryptoCarl, MariaRD, AussieAnna and 3 others
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MASHdoc_SA
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San Antonio, TX
Jan 20, 2026 at 8:51 AM#17

hank_denver's experience with Liver biopsy changes on resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I am on a different medication. But the overall trajectory has been remarkably similar. Down 47 lbs in 12 months.

One thing I would add that hank_denver did not mention: my sleep quality improved dramatically.

39 2TrialTracker_MD, JennaRN, LabKate and 36 others
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Dr.ObesityLA
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Jan 20, 2026 at 9:08 AM#18

Bookmarked 📌 The Liver biopsy changes info in this thread is essential. Coming back to this for sure.

36 23tampaLisa73, KarenAZ_mom, zoe_NC and 33 others
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james_edin
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Jan 20, 2026 at 9:25 AM#19

Clinical perspective on Liver biopsy changes on semaglutide :

I have managed over 200 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

15 3oliver_london, tane_welly, Dr.PathRoch and 12 others
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anders_CPH
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Jan 20, 2026 at 9:42 AM#20

Subscribing to this thread. Liver biopsy changes on is exactly what I've been researching. 🙏

11 3ChrisMacros, KetoKyle, CanadaChris and 8 others
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