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ForumsSide Effects & ManagementGallbladder disease risk — cholelithiasis data from clinical trials Page 3

Gallbladder disease risk — cholelithiasis data from clinical trials

PharmacoVig_BOS Thu, Mar 12, 2026 at 12:51 PM 12 replies 266 viewsPage 3 of 3
Admin
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Mar 12, 2026 at 5:06 PM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

12 23PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 9 others
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DataDave
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Mar 12, 2026 at 5:23 PM#12

Slightly tangential to Gallbladder disease risk but TirzTom reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

19 10mike_nyc, VendorMark, COA_Karl and 16 others
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traveltech_sara
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Mar 12, 2026 at 5:40 PM#13
hannah_MT said:
Follow-up question: how long did you wait before increasing your dose

This is exactly right. hannah_MT articulated what I have been trying to explain to my doctor for months. The Gallbladder disease risk aspect is the most important factor.

Last edited: Mar 12, 2026 at 8:40 PM
47 5wanda_boise, NurseAsh_DET, BenResearch_OR and 44 others
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oliver_london
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Mar 12, 2026 at 5:57 PM#14

Saving this for reference. Top-tier content.

13 22jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 10 others
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anders_CPH
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Mar 12, 2026 at 6:14 PM#15

Adding my data to this Gallbladder disease risk discussion:

MetricBaselineMonth 4Month 8
Weight254 lbs224 lbs199 lbs
A1C6.8%6.2%5.4%
hsCRP8.03.01.2

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.

25 8ChrisMacros, KetoKyle, CanadaChris and 22 others
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