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ForumsMASH / Liver DiseaseDe novo lipogenesis reduction on GLP-1 — looking for input Page 5

De novo lipogenesis reduction on GLP-1 — looking for input

kate.chem Wed, Dec 31, 2025 at 11:30 AM 30 replies 896 viewsPage 5 of 6
PeptideChemSF
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Jan 2024
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Dec 31, 2025 at 6:35 PM#21

Exactly this. My pharmacist said the same thing about De novo lipogenesis.

32 18steve_okc, dave_SLC, FDA_TrackerJim and 29 others
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chris_chi24
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Sep 2024
Chicago, IL
Dec 31, 2025 at 6:52 PM#22
Dr.SurgeonPGH said:
De novo lipogenesis reduction on is not that straightforward in my experience

This is exactly right. Dr.SurgeonPGH articulated what I have been trying to explain to my friends for months. The De novo lipogenesis aspect is what made the difference for me.

33 21MounjBrad, nick_newbie, DadBodDave and 30 others
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JakeBK_lifts
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Dec 31, 2025 at 7:09 PM#23

+1. This mirrors my journey exactly. The De novo lipogenesis discussion here is so valuable.

Last edited: Dec 31, 2025 at 9:09 PM
27 14LabKate, kate.chem, DataDave and 24 others
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claudia_zurich
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Dec 31, 2025 at 7:26 PM#24
nancy_portland said:
pat_auckland described it perfectly

This is exactly right. nancy_portland articulated what I have been trying to explain to my doctor for months. The De novo lipogenesis aspect is the most important factor.

Last edited: Jan 1, 2026 at 1:26 AM
39 24alex_tucson, kevin_tulsa, Dr.PainCLE and 36 others
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Dr.EndoEP
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Oct 2024
El Paso, TX
Dec 31, 2025 at 7:43 PM#25

Subscribing to this thread. De novo lipogenesis is exactly what I've been researching. 🙏

36 5LindaRN_retired, tommy_boulder, hyun_seoul and 33 others
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