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ForumsMASH / Liver DiseaseFibrosis regression on GLP-1 — need advice Page 2

Fibrosis regression on GLP-1 — need advice

COA_Karl Sat, Dec 27, 2025 at 4:16 AM 12 replies 679 viewsPage 2 of 3
lori_vegas
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Dec 27, 2025 at 7:06 AM#6

Saving this for reference. Top-tier content.

Last edited: Dec 27, 2025 at 9:06 AM
4 12amy_econ_NJ, bbq_ray_KC, oliver_london and 1 other
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JessicaH_TX
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Dec 27, 2025 at 7:23 AM#7

Slightly tangential to Fibrosis regression on but KristenIndy reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

7 4sarah_TO, wendy_avl, jason_paloalto and 4 others
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TomTeleRx
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Delaware
Dec 27, 2025 at 7:40 AM#8

+1 to KristenIndy. Especially the point about "A few questions about your Fibrosis regr..." — I have seen the same in my own experience with Fibrosis regression on.

Last edited: Dec 27, 2025 at 8:40 AM
45 20LibrarianMeg, bri_stats, pete_manc_UK and 42 others
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KetoKyle
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Dec 27, 2025 at 7:57 AM#9

Dr.EndoIndy — that is really helpful context on Fibrosis regression on. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

25 22Dr.GastroMayo, JakeBK_lifts, DerekSJ_a1c and 22 others
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Dr.ReproEndo
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Dec 27, 2025 at 8:14 AM#10

To answer TomTeleRx's question specifically:

From a clinical standpoint, Fibrosis regression on GLP-1 is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

7 9carl_compliance, DanielChem_CHI, marco_milano and 4 others
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