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ForumsProgress & Lab Results12-month metabolic panel comparison — before and after GLP-1 Page 3

12-month metabolic panel comparison — before and after GLP-1

DataDave Fri, Mar 13, 2026 at 4:31 PM 22 replies 610 viewsPage 3 of 5
dan_philly
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Jul 2024
Philadelphia, PA
Mar 13, 2026 at 8:46 PM#11

+1 to PurityPaulOR. Especially the point about "Re: 12-month metabolic panel — the effec..." — I have seen the same in my own experience with 12-month metabolic panel.

Last edited: Mar 13, 2026 at 11:46 PM
40 3DadBodDave, AmyNC_wife, SkepticalSean and 37 others
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mike_mealprep
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Jul 2024
Chicago, IL
Mar 13, 2026 at 9:03 PM#12

Want to share my personal experience related to 12-month metabolic panel since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 279 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 44 lbs, my labs have normalized, and I am off 2 of my 3 medications. The 12-month metabolic aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Last edited: Mar 14, 2026 at 3:03 AM
15 20newstart_MO, mia_MS2, LeilaHI and 12 others
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jason_sac26
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Jan 2026
Sacramento, CA
Mar 13, 2026 at 9:20 PM#13

hans_munich — that is really helpful context on 12-month metabolic panel. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

Last edited: Mar 13, 2026 at 11:20 PM
50 23stefan_berlin, Dr.EM_Chicago, pete_RVA and 47 others
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NurseLeah_Nash
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Sep 2024
Nashville, TN
Mar 13, 2026 at 9:37 PM#14

To answer mike_mealprep's question specifically:

From a clinical standpoint, 12-month metabolic panel is something I discuss with patients regularly.

The short answer: discuss this specific situation with your prescribing provider.

The longer answer involves weighing the risk-benefit ratio for your individual situation, which I am happy to elaborate on if helpful.

1 7Dr.KarenChen
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SarahChen_PharmD
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Dec 2023
San Diego, CA
Mar 13, 2026 at 9:54 PM#15

Saving this for reference. Quality thread.

28 12robert_kc, dan_philly, MeganSA_TX and 25 others
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