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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab Results12-month metabolic panel comparison — before and after GLP-1 Page 4

12-month metabolic panel comparison — before and after GLP-1

DataDave Fri, Mar 13, 2026 at 4:31 PM 22 replies 610 viewsPage 4 of 5
DataDave
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Mar 13, 2026 at 10:11 PM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on 12-month metabolic panel.

To answer mike_mealprep: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Mar 13, 2026 at 11:11 PM
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dave_SLC
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Mar 13, 2026 at 10:28 PM#17

Relevant to 12-month metabolic panel — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 229 → 99 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

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LarryQC_SD
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Mar 13, 2026 at 10:45 PM#18

100%. My provider said the same thing about 12-month metabolic.

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Dr.RenalNash
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Mar 13, 2026 at 11:02 PM#19

Slightly tangential to 12-month metabolic panel but dan_philly reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Mar 14, 2026 at 4:02 AM
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stefan_berlin
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Mar 13, 2026 at 11:19 PM#20
DataDave said:
Thank you all for the thoughtful replies on 12-month metabolic panel

This is exactly right. DataDave articulated what I have been trying to explain to my doctor for months. The 12-month metabolic panel aspect is the most important factor.

Last edited: Mar 14, 2026 at 2:19 AM
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