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ForumsMASH / Liver DiseaseQuit drinking AND started sema - liver is thanking me — March 2026 Page 3

Quit drinking AND started sema - liver is thanking me — March 2026

chris_chi24 Fri, Nov 7, 2025 at 7:39 AM 21 replies 1,128 viewsPage 3 of 5
HPLC_Greg
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Feb 2024
Research Triangle, NC
Nov 7, 2025 at 11:54 AM#11

+1 to julia.endo. Especially the point about "Re: Quit drinking AND started sema — the..." — I have seen the same in my own experience with Quit drinking AND started.

4 5SallyK_inj, CryptoCarl, MariaRD and 1 other
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labquiet_amy
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Mar 2024
Cambridge, MA
Nov 7, 2025 at 12:11 PM#12

Want to share my personal experience related to Quit drinking AND started sema since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 264 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 64 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Quit drinking AND aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

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tyler_CSCS
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Phoenix, AZ
Nov 7, 2025 at 12:28 PM#13

Dr.NephBHM_UK — that is really helpful context on Quit drinking AND started. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

Last edited: Nov 7, 2025 at 2:28 PM
26 20Dr.SportsMedIN, amy_econ_NJ, bbq_ray_KC and 23 others
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TrialTracker_MD
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Jan 2024
Maryland
Nov 7, 2025 at 12:45 PM#14

To answer labquiet_amy's question specifically:

From a clinical standpoint, Quit drinking AND started sema is well-supported by the literature.

The short answer: follow the standard titration protocol and reassess at 4-6 weeks.

The longer answer involves pharmacokinetic considerations around steady-state concentrations, which I am happy to elaborate on if helpful.

Last edited: Nov 7, 2025 at 5:45 PM
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SandraNC_45
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Charlotte, NC
Nov 7, 2025 at 1:02 PM#15

Saving this for reference. Top-tier content.

Last edited: Nov 7, 2025 at 6:02 PM
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