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ForumsSemaglutide (Ozempic / Wegovy)Why does sema make me SO tired?? — my results so far Page 5

Why does sema make me SO tired?? — my results so far

tommy_boulder Mon, Apr 7, 2025 at 3:39 AM 31 replies 1,915 viewsPage 5 of 7
AttorneyGrant
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Apr 7, 2025 at 10:44 AM#21

DeniseRN_TPA — that is really helpful context on Why does sema make me SO. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

34 11Dr.SleepRoch, laura_annarbor, JenMemphis and 31 others
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VendorMark
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Apr 7, 2025 at 11:01 AM#22

To answer emily_PDX's question specifically:

From a clinical standpoint, Why does sema make me SO is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

Last edited: Apr 7, 2025 at 1:01 PM
41 6KristenIndy, MarkLI_maint, Dr.PeteFamMed and 38 others
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Dr.EndoIndy
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Apr 7, 2025 at 11:18 AM#23

Thank you AttorneyGrant! This is incredibly helpful. Bookmarking for later. 🙏

33 2marcus_mpls, DeniseRN_TPA, SandraNC_45 and 30 others
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BiostatsBrad
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Apr 7, 2025 at 11:35 AM#24

Relevant to Why does sema make me SO — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 229 → 99 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

21 11james_edin, FranDenver, Dr.BariatricHTX and 18 others
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SkepticalSean
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Apr 7, 2025 at 11:52 AM#25

Slightly tangential to Why does sema make me SO but AttorneyGrant reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

25 23Dr.LipidDallas, alex_tucson, kevin_tulsa and 22 others
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