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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseHas anyone dealt with alt normalization rates on glp-1? Page 5

Has anyone dealt with alt normalization rates on glp-1?

laura_annarbor Tue, Oct 14, 2025 at 9:24 PM 23 replies 1,414 viewsPage 5 of 5
bri_stats
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Seattle, WA
Oct 15, 2025 at 4:29 AM#21

Want to share my personal experience related to Has anyone dealt with alt since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 266 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 41 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Has anyone dealt aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

31 20sarah_nash92, FitDadDave, RunnerRach and 28 others
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mike_mod
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Oct 15, 2025 at 4:46 AM#22

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

Last edited: Oct 15, 2025 at 6:46 AM
48 9TomTeleRx, DoseLogDan, SleepFixSam and 45 others
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HPLC_Greg
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Feb 2024
Research Triangle, NC
Oct 15, 2025 at 5:03 AM#23

Adding my data to this Has anyone dealt with alt discussion:

MetricBaselineMonth 5Month 6
Weight268 lbs228 lbs203 lbs
A1C7.2%6.0%5.2%
hsCRP7.04.01.0

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.

36 8RetaRick_CA, JenPlateau, SallyK_inj and 33 others
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tane_welly
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Wellington, NZ
Oct 15, 2025 at 5:20 AM#24

Dr.EndoIndy — wow. This community is amazing.

31 23marco_milano, pam_columbus, nick_SD_fit and 28 others
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josh_phd_bmore
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Baltimore, MD
Oct 15, 2025 at 5:37 AM#25
SkepticalSean said:
Has anyone dealt with alt is exactly what I've been researching

This is exactly right. SkepticalSean articulated what I have been trying to explain to my friends for months. The Has anyone dealt with alt aspect is what made the difference for me.

17 3tampaLisa73, KarenAZ_mom, zoe_NC and 14 others
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