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ForumsProgress & Lab ResultsCRP from 12.4 to 0.8 — inflammation before and after GLP-1 Page 5

CRP from 12.4 to 0.8 — inflammation before and after GLP-1

DataDave Wed, Feb 25, 2026 at 4:32 PM 32 replies 970 viewsPage 5 of 7
Dr.MetabolicMD
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Feb 25, 2026 at 11:37 PM#21

Want to share my personal experience related to CRP from 12.4 to 0.8 since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 278 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 73 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The CRP from 12.4 to 0.8 aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Feb 26, 2026 at 1:37 AM
48 22SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 45 others
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mike_mod
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Feb 25, 2026 at 11:54 PM#22

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

Last edited: Feb 26, 2026 at 1:54 AM
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HPLC_Greg
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Feb 26, 2026 at 12:11 AM#23

Adding my data to this CRP from 12.4 to 0.8 discussion:

MetricBaselineMonth 5Month 6
Weight260 lbs235 lbs215 lbs
A1C6.4%6.0%5.2%
hsCRP4.04.01.0

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

40 9RetaRick_CA, JenPlateau, SallyK_inj and 37 others
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Dr.GastroMayo
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Feb 26, 2026 at 12:28 AM#24

claudia_zurich — wow. This community is amazing.

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rick_sfbay
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Feb 26, 2026 at 12:45 AM#25
tony_orlando said:
8 is exactly what I've been researching

This is exactly right. tony_orlando articulated what I have been trying to explain to my friends for months. The CRP from 12.4 to 0.8 aspect is what made the difference for me.

28 13Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 25 others
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