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ForumsProgress & Lab Results[PREMIUM] 18-month transformation — 127 lbs lost — full photo set Page 3

[PREMIUM] 18-month transformation — 127 lbs lost — full photo set

JakeSmashed95 Thu, Feb 19, 2026 at 3:07 AM 25 replies 641 viewsPage 3 of 5
rick_sfbay
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Jan 2025
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Feb 19, 2026 at 7:22 AM#11

DataDave — wow. This community is amazing.

4 18mike_mealprep, NicoleRaleigh, james_edin and 1 other
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MeganSA_TX
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Jun 2024
San Antonio, TX
Feb 19, 2026 at 7:39 AM#12

Slightly tangential to 18-month transformation but JakeSmashed95 reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

43 1julia.endo, JessicaM_2024, TomFromTexas and 40 others
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SallyK_inj
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Jul 2024
Iowa
Feb 19, 2026 at 7:56 AM#13

Thanks for sharing this, JakeSmashed95. A few questions about your 18-month transformat experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about 18-month transf?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Feb 19, 2026 at 8:56 AM
30 16oliver_london, tane_welly, Dr.PathRoch and 27 others
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JakeSmashed95
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Aug 2024
Arkansas
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Feb 19, 2026 at 8:13 AM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on 18-month transformation .

To answer MeganSA_TX: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

13 18Dr.LipidDallas, alex_tucson, kevin_tulsa and 10 others
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dan_philly
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Jul 2024
Philadelphia, PA
Feb 19, 2026 at 8:30 AM#15

Relevant to 18-month transformation 127 — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 229 → 99 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

11 0EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 8 others
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