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Evidence-based GLP-1 & peptide discussion since 2023
ForumsExercise & Body CompositionHas anyone dealt with resistance training prevents 73% lean mass loss on semaglutide? Page 3

Has anyone dealt with resistance training prevents 73% lean mass loss on semaglutide?

SaraMom3 Fri, Aug 1, 2025 at 6:43 PM 11 replies 1,220 viewsPage 3 of 3
KarenAZ_mom
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Aug 2024
Scottsdale, AZ
Aug 1, 2025 at 10:58 PM#11

quinn_sf — wow. This community is amazing.

28 19anna.melb_AU, mark_tokyo, hans_munich and 25 others
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ZaraB_AL
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Jan 2025
Alabama
Aug 1, 2025 at 11:15 PM#12

Slightly tangential to Has anyone dealt with but SaraMom3 reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Aug 2, 2025 at 12:15 AM
29 3KevinCompounds, TirzTom, TrialTracker_MD and 26 others
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hannah_MT
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Feb 2026
Bozeman, MT
Aug 1, 2025 at 11:32 PM#13

Thanks for sharing this, SaraMom3. A few questions about your Has anyone dealt experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about Has anyone deal?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

43 12MaxMetOK, MounjBrad, nick_newbie and 40 others
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SaraMom3
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Aug 2024
Ohio
Aug 1, 2025 at 11:49 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with.

To answer ZaraB_AL: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

38 13CanadaChris, ZaraB_AL, JakeSmashed95 and 35 others
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anders_CPH
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Copenhagen, DK
Aug 2, 2025 at 12:06 AM#15

Relevant to Has anyone dealt with — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 225 → 95 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Aug 2, 2025 at 4:06 AM
8 5ChrisMacros, KetoKyle, CanadaChris and 5 others
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