Jan 20, 2026 at 5:15 PM#11
fiona_glasgow — wow. I've been looking for this exact info for weeks.
Last edited: Jan 20, 2026 at 8:15 PM
39 8TirzTom, TrialTracker_MD, JennaRN and 36 others
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Jan 20, 2026 at 5:32 PM#12
Slightly tangential to TMI but the constipation but NauseaFreeNow reminded me — has anyone else noticed changes in their alcohol tolerance?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Last edited: Jan 20, 2026 at 6:32 PM
14 11Dr.PulmRoch, maya_sedona, stefan_berlin and 11 others
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Jan 20, 2026 at 5:49 PM#13
Thanks for sharing this, NauseaFreeNow. A few questions about your TMI but the experience:
- What dose did you start at?
- How long before you noticed side effects improving?
- Did your provider have any specific recommendations about TMI but the?
I am in a similar boat and trying to learn from others' experiences before my next appointment.
Last edited: Jan 20, 2026 at 8:49 PM
16 15TomTeleRx, DoseLogDan, SleepFixSam and 13 others
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View ResultsJan 20, 2026 at 6:06 PM#14
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on TMI but the constipation.
To answer BethLabQueen: I get my labs done through Quest every 3 months.
Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Last edited: Jan 20, 2026 at 10:06 PM
17 12lori_vegas, Dr.PulmRoch, maya_sedona and 14 others
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Jan 20, 2026 at 6:23 PM#15
Relevant to TMI but the constipation is — here is my latest bloodwork comparison:
Key improvements: A1C 8.0% → 5.3%, triglycerides 223 → 93 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Last edited: Jan 20, 2026 at 7:23 PM
40 12FranDenver, Dr.BariatricHTX, LindaRN_retired and 37 others
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