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ForumsSide Effects & ManagementTMI but the constipation is REAL Page 8

TMI but the constipation is REAL

NauseaFreeNow Tue, Jan 20, 2026 at 1:00 PM 37 replies 1,223 viewsPage 8 of 8
LindaRN_retired
Member
189
890
Dec 2024
Sarasota, FL
Jan 21, 2026 at 12:20 AM#36

Want to share my personal experience related to TMI but the constipation is since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 284 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 54 lbs, my labs have normalized, and I am off 2 of my 3 medications. The TMI but the aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Last edited: Jan 21, 2026 at 3:20 AM
26 19DataDave, Dr.GutHealth, amsterdam_pete and 23 others
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lucas_SP_BR
Member
456
1,890
Jun 2024
São Paulo, BR
Jan 21, 2026 at 12:37 AM#37

NauseaFreeNow — that is really helpful context on TMI but the constipation. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

27 13Dr.ObesityLA, NurseKim_ATL, paul_denver and 24 others
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ingrid_STO
Member
345
1,456
Jul 2024
Stockholm, SE
Jan 21, 2026 at 12:54 AM#38

Want to share my personal experience related to TMI but the constipation is since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 256 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 61 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The TMI but the aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

16 24MikeFit_NJ, InsuranceTom, WendyG_ATL and 13 others
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hank_denver
Member
278
1,234
Sep 2024
Denver, CO
Jan 21, 2026 at 1:11 AM#39

lucas_SP_BR — that is really helpful context on TMI but the constipation. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

28 10fiona_VT, denise_HTX, raj_cambridge and 25 others
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RickReta_CO
Member
312
1,234
Jan 2025
Colorado
Jan 21, 2026 at 1:28 AM#40

Want to share my personal experience related to TMI but the constipation is since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 273 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 68 lbs, my labs have normalized, and I am off 2 of my 3 medications. The TMI but the aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

23 14LindaRN_retired, tommy_boulder, hyun_seoul and 20 others
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