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ForumsSemaglutide (Ozempic / Wegovy)STEP 1-5 trials comprehensive summary — my results so far Page 5

STEP 1-5 trials comprehensive summary — my results so far

ben_calgary Sun, Jan 19, 2025 at 10:35 AM 40 replies 2,086 viewsPage 5 of 8
tane_welly
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Sep 2024
Wellington, NZ
Jan 19, 2025 at 5:40 PM#21

JenPlateau — that is really helpful context on STEP 1-5 trials. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

Last edited: Jan 19, 2025 at 8:40 PM
11 18GraceAZ_72, carl_compliance, DanielChem_CHI and 8 others
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roxy_nash
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Dec 2024
Nashville, TN
Jan 19, 2025 at 5:57 PM#22

To answer rick_sfbay's question specifically:

From a clinical standpoint, STEP 1-5 trials comprehensive is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

20 2roxy_nash, tony_orlando, Dr.NephBHM_UK and 17 others
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CryptoCarl
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May 2024
Arizona
Jan 19, 2025 at 6:14 PM#23

Thank you tane_welly! This is incredibly helpful. Bookmarking for later. 🙏

33 3AussieAnna, BethLabQueen, ChrisMacros and 30 others
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Dr.PeteFamMed
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Jan 2024
Minneapolis, MN
Jan 19, 2025 at 6:31 PM#24

Relevant to STEP 1-5 trials comprehensive — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 233 → 103 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

25 10Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 22 others
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tampaLisa73
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Oct 2024
Tampa, FL
Jan 19, 2025 at 6:48 PM#25

Slightly tangential to STEP 1-5 trials but tane_welly reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Jan 19, 2025 at 7:48 PM
4 2TomFromTexas, mike.trainer_LA, sarah_nash92 and 1 other
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