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ForumsMASH / Liver DiseaseMASH biomarker panel — need advice Page 3

MASH biomarker panel — need advice

carl_compliance Fri, Aug 8, 2025 at 2:44 PM 14 replies 1,207 viewsPage 3 of 3
raj_cambridge
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Aug 8, 2025 at 6:59 PM#11

+1 to BethLabQueen. Especially the point about "Re: MASH biomarker panel need — the sub..." — I have seen the same in my own experience with MASH biomarker panel .

8 5SleepFixSam, PurityPaulOR, MaxMetOK and 5 others
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TirzTom
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Aug 8, 2025 at 7:16 PM#12

Want to share my personal experience related to MASH biomarker panel need since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 277 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 67 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The MASH biomarker panel aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

9 5tom_AK, josh_phd_bmore, roxy_nash and 6 others
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anna.melb_AU
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Aug 8, 2025 at 7:33 PM#13

Dr.DermMIA — that is really helpful context on MASH biomarker panel . Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

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GenomicsKate
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Aug 8, 2025 at 7:50 PM#14

To answer TirzTom's question specifically:

From a clinical standpoint, MASH biomarker panel need is well-supported by the literature.

The short answer: follow the standard titration protocol and reassess at 4-6 weeks.

The longer answer involves pharmacokinetic considerations around steady-state concentrations, which I am happy to elaborate on if helpful.

38 10Dr.PeteFamMed, claudia_zurich, nancy_portland and 35 others
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Dr.RaviCardio
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Aug 8, 2025 at 8:07 PM#15

Saving this for reference. Top-tier content.

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