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ForumsProgress & Lab Results[PREMIUM] Couple's transformation — husband and wife both on GLP-1 (before/after) Page 3

[PREMIUM] Couple's transformation — husband and wife both on GLP-1 (before/after)

AmyNC_wife Thu, Feb 5, 2026 at 5:01 PM 25 replies 850 viewsPage 3 of 5
pam_stl
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St. Louis, MO
Feb 5, 2026 at 9:16 PM#11

+1 to JennaRN. Especially the point about "Re: Couple's transformation — the effec..." — I have seen the same in my own experience with Couple's transformation .

9 6Dr.ObesityMed, HealthEcon_DC, PedsEndoPhilly and 6 others
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nick_SD_fit
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Sep 2024
San Diego, CA
Feb 5, 2026 at 9:33 PM#12

Want to share my personal experience related to Couple's transformation since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 279 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 49 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Couple's transformat aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

21 0Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 18 others
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tammy_FL
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Tampa, FL
Feb 5, 2026 at 9:50 PM#13

Dr.EndoIndy — that is really helpful context on Couple's transformation . Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

Last edited: Feb 6, 2026 at 3:50 AM
11 22kevin_tulsa, Dr.PainCLE, mike_mealprep and 8 others
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hyun_seoul
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Jul 2024
Seoul, KR
Feb 5, 2026 at 10:07 PM#14

To answer nick_SD_fit's question specifically:

From a clinical standpoint, Couple's transformation is something I discuss with patients regularly.

The short answer: discuss this specific situation with your prescribing provider.

The longer answer involves weighing the risk-benefit ratio for your individual situation, which I am happy to elaborate on if helpful.

34 23BariatricNurseD, MASHdoc_SA, GenomicsKate and 31 others
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Dr.ObesityMed
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Feb 5, 2026 at 10:24 PM#15

Saving this for reference. Quality thread.

10 1A1cHero_PHX, Dr.RenalNash, LipidDoc_ATL and 7 others
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