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ForumsMASH / Liver DiseaseEfinopegdutide MASH data — my results so far

Efinopegdutide MASH data — my results so far

tony_orlando Wed, Jul 9, 2025 at 5:15 AM 11 replies 1,314 viewsPage 1 of 3
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tony_orlando
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Nov 2024
Orlando, FL
Jul 9, 2025 at 6:40 AM#1

Hi all, brand new here. My NP just prescribed semaglutide and I have a question about efinopegdutide mash data my results so.

Sorry if this has been asked before — I did try searching but the amount of information here is overwhelming (in a good way). I am on day 3 and everything is new to me.

Any guidance appreciated. You all seem really knowledgeable and I am glad I found this community.

26 21NauseaFreeNow, SteveThurs, B12Beth and 23 others
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CarlaRPh_TPA
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Tampa, FL
Jul 9, 2025 at 6:57 AM#2

tony_orlando's experience with Efinopegdutide MASH data resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I started 3 months later. But the overall trajectory has been remarkably similar. Down 66 lbs in 11 months.

One thing I would add that tony_orlando did not mention: the mental health improvements were just as significant.

20 11ricardo_MIA, BrianDallas92, labquiet_amy and 17 others
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chris_chi24
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Sep 2024
Chicago, IL
Jul 9, 2025 at 7:14 AM#3

Thanks for sharing this, tony_orlando. A few questions about your Efinopegdutide MASH experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about Efinopegdutide?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Jul 9, 2025 at 10:14 AM
38 20MaxMetOK, MounjBrad, nick_newbie and 35 others
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tony_orlando
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Nov 2024
Orlando, FL
Jul 9, 2025 at 7:31 AM#4

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Efinopegdutide MASH data .

To answer chris_chi24: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Jul 9, 2025 at 8:31 AM
1 20CanadaChris
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Dr.AddMedPHL
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Jul 9, 2025 at 7:48 AM#5

Relevant to Efinopegdutide MASH data my — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 219 → 119 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Jul 9, 2025 at 9:48 AM
44 9JessicaM_2024, TomFromTexas, mike.trainer_LA and 41 others
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