HPLC_Greg said:

my doc mentioned it and i panicked

I respect HPLC_Greg perspective but I think this oversimplifies things a bit. Re: Has anyone dealt with what — the effect size varies considerably by population.

I am not saying HPLC_Greg wrong entirely — just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.

Relevant to Has anyone dealt with what — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 243 → 113 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Thank you Dr.KarenChen! This is incredibly helpful. Bookmarking for later. 🙏

Slightly tangential to Has anyone dealt with but A1cHero_PHX reminded me — has the insurance landscape changed recently?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍