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ForumsExercise & Body CompositionCrossFit on tirzepatide — what worked for you?

CrossFit on tirzepatide — what worked for you?

labquiet_amy Wed, Apr 16, 2025 at 2:25 AM 49 replies 2,245 viewsPage 1 of 10
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labquiet_amy
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Apr 16, 2025 at 3:50 AM#1

Hi all, brand new here. My NP just prescribed semaglutide and I have a question about crossfit on tirzepatide what worked for.

Sorry if this has been asked before — I did try searching but the amount of information here is overwhelming (in a good way). I am on day 3 and everything is new to me.

Any guidance appreciated. You all seem really knowledgeable and I am glad I found this community.

9 11TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 6 others
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VendorMark
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Apr 16, 2025 at 4:07 AM#2

labquiet_amy's experience with CrossFit on tirzepatide resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I titrated faster. But the overall trajectory has been remarkably similar. Down 36 lbs in 11 months.

One thing I would add that labquiet_amy did not mention: the relationship with food fundamentally changed.

Last edited: Apr 16, 2025 at 6:07 AM
20 16KristenIndy, MarkLI_maint, Dr.PeteFamMed and 17 others
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MarkLI_maint
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Apr 16, 2025 at 4:24 AM#3

Thanks for sharing this, labquiet_amy. A few questions about your CrossFit on experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about CrossFit on?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

9 14HPLC_Greg, LibrarianMeg, bri_stats and 6 others
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labquiet_amy
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Apr 16, 2025 at 4:41 AM#4

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on CrossFit on tirzepatide .

To answer MarkLI_maint: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

33 12bri_stats, pete_manc_UK, anna.melb_AU and 30 others
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Dr.NateNeph
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Apr 16, 2025 at 4:58 AM#5

Relevant to CrossFit on tirzepatide what — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 249 → 119 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

39 11RickReta_CO, PharmHunterJen, TomTeleRx and 36 others
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