Same experience here with Semaglutide and gut. RetaRick_CA described it perfectly.

Dr.RenalNash said:

Dad of 2 checking in — I started at 261 lbs and felt like I would tried everything

I respect Dr.RenalNash perspective but I think this oversimplifies things a bit. Re: Semaglutide and gut microbiome — the subgroup analyses show meaningful heterogeneity.

I am not saying Dr.RenalNash wrong entirely — just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.

Reading this thread on Semaglutide and gut hits close to home. Night shift nurse — I started at 287 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 62 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Semaglutide and gut — take the leap. It was the best health decision I have ever made. ❤️

Bookmarked 📌 The Semaglutide and gut info in this thread is essential. Coming back to this for sure.

GraceAZ_72 — that is really helpful context on Semaglutide and gut. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.