Semaglutide and gut microbiome changes — looking for input — Page 7 | Semaglutide (Ozempic / Wegovy)

Dr.Martinez

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Jun 17, 2024 at 9:02 AM#31

To answer Dr.ObesityMed's question specifically:

From a clinical standpoint, Semaglutide and gut microbiome is well-supported by the literature.

The short answer: follow the standard titration protocol and reassess at 4-6 weeks.

The longer answer involves pharmacokinetic considerations around steady-state concentrations, which I am happy to elaborate on if helpful.

Last edited: Jun 17, 2024 at 2:02 PM

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Dr.NutriCornell

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Jun 17, 2024 at 9:19 AM#32

Just wanted to say — for anyone reading this Semaglutide and gut thread who is feeling discouraged: it gets better. The first month are the hardest. Hang in there. 💪

Last edited: Jun 17, 2024 at 11:19 AM

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NurseAsh_DET

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Jun 17, 2024 at 9:36 AM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Semaglutide and gut.

To answer NurseAsh_DET: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

26 7BrianDallas92, labquiet_amy, emily_PDX and 23 others

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Dr.LeslieOBGYN

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Jun 17, 2024 at 9:53 AM#34

Just wanted to say — for anyone reading this Semaglutide and gut thread who is feeling discouraged: it gets better. The first 6 weeks are the hardest. Hang in there. 💪

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