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ForumsSide Effects & ManagementAcid reflux/GERD worsening on GLP-1 — my results so far Page 3

Acid reflux/GERD worsening on GLP-1 — my results so far

JessicaM_2024 Wed, Oct 15, 2025 at 7:30 AM 40 replies 1,616 viewsPage 3 of 8
RickReta_CO
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312
1,234
Jan 2025
Colorado
Oct 15, 2025 at 11:45 AM#11

Thank you rachel_ABQ! This is incredibly helpful. Taking this to my next appointment. 🙏

Last edited: Oct 15, 2025 at 4:45 PM
18 15matt_MKE, Dr.ReproEndo, lucas_SP_BR and 15 others
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DerekSJ_a1c
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Aug 2024
San Jose, CA
Oct 15, 2025 at 12:02 PM#12

Slightly tangential to Acid reflux/GERD but JessicaM_2024 reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Oct 15, 2025 at 5:02 PM
25 0Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 22 others
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james_edin
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Sep 2024
Edinburgh, UK
Oct 15, 2025 at 12:19 PM#13

Thanks for sharing this, JessicaM_2024. A few questions about your Acid reflux/GERD experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Acid reflux/GER?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

36 23tane_welly, Dr.PathRoch, mona_PHX and 33 others
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JessicaM_2024
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823
3,456
Mar 2024
Portland, OR
Oct 15, 2025 at 12:36 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Acid reflux/GERD.

To answer DerekSJ_a1c: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

30 15Dr.PainCLE, mike_mealprep, NicoleRaleigh and 27 others
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josh_phd_bmore
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Jul 2024
Baltimore, MD
Oct 15, 2025 at 12:53 PM#15

Adding my data to this Acid reflux/GERD discussion:

MetricBaselineMonth 3Month 8
Weight246 lbs236 lbs201 lbs
A1C7.0%5.8%5.4%
hsCRP5.02.01.2

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

47 16tampaLisa73, KarenAZ_mom, zoe_NC and 44 others
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