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ForumsSide Effects & ManagementAcid reflux/GERD worsening on GLP-1 — my results so far Page 4

Acid reflux/GERD worsening on GLP-1 — my results so far

JessicaM_2024 Wed, Oct 15, 2025 at 7:30 AM 40 replies 1,616 viewsPage 4 of 8
SallyK_inj
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Jul 2024
Iowa
Oct 15, 2025 at 1:10 PM#16

Just wanted to say — for anyone reading this Acid reflux/GERD thread who is feeling discouraged: it gets better. The first few weeks are the hardest. Hang in there. 💪

3 16amy_econ_NJ, bbq_ray_KC, oliver_london
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MASHdoc_SA
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Aug 2024
San Antonio, TX
Oct 15, 2025 at 1:27 PM#17

JessicaM_2024's experience with Acid reflux/GERD resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I started 3 months later. But the overall trajectory has been remarkably similar. Down 58 lbs in 13 months.

One thing I would add that JessicaM_2024 did not mention: the mental health improvements were just as significant.

12 6TrialTracker_MD, JennaRN, LabKate and 9 others
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NurseKim_ATL
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Oct 15, 2025 at 1:44 PM#18

Saving this for reference. Top-tier content.

11 16ingrid_STO, pete_nash, hank_denver and 8 others
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LindaRN_retired
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Dec 2024
Sarasota, FL
Oct 15, 2025 at 2:01 PM#19

As a pharmacist, I want to add some clinical context to this discussion on Acid reflux/GERD worsening on GLP-1 my.

Building on what JessicaM_2024 said — the evidence base here is robust. The key publications to reference are from the STEP program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
Last edited: Oct 15, 2025 at 5:01 PM
27 18LondonLisa, mike_nyc, VendorMark and 24 others
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pam_stl
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Oct 2024
St. Louis, MO
Oct 15, 2025 at 2:18 PM#20

Subscribing to this thread. Acid reflux/GERD is exactly what I've been researching. 🙏

44 24RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 41 others
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