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ForumsSide Effects & ManagementAcid reflux/GERD worsening on GLP-1 — my results so far Page 6

Acid reflux/GERD worsening on GLP-1 — my results so far

JessicaM_2024 Wed, Oct 15, 2025 at 7:30 AM 40 replies 1,616 viewsPage 6 of 8
alex_tucson
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Oct 15, 2025 at 4:00 PM#26

Just wanted to say — for anyone reading this Acid reflux/GERD thread who is feeling discouraged: it gets better. The first 6 weeks are the hardest. Hang in there. 💪

Last edited: Oct 15, 2025 at 6:00 PM
4 0emily_PDX, Dr.SleepRoch, laura_annarbor and 1 other
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CarlaRPh_TPA
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Oct 15, 2025 at 4:17 PM#27

Slightly tangential to Acid reflux/GERD but mike_mod reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

23 14ricardo_MIA, BrianDallas92, labquiet_amy and 20 others
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ben_calgary
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Oct 2024
Calgary, CA
Oct 15, 2025 at 4:34 PM#28

Agreed. My doctor said the same thing about Acid reflux/GERD.

Last edited: Oct 15, 2025 at 10:34 PM
37 7ZaraB_AL, JakeSmashed95, NauseaFreeNow and 34 others
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Oct 15, 2025 at 4:51 PM#29

Want to share my personal experience related to Acid reflux/GERD worsening on since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 280 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 70 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Acid reflux/GERD aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

31 16BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 28 others
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carl_compliance
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Nov 2024
Raleigh, NC
Oct 15, 2025 at 5:08 PM#30

Clinical perspective on Acid reflux/GERD worsening on GLP-1 my:

I have managed ~150 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

Last edited: Oct 15, 2025 at 8:08 PM
43 24dave_SLC, FDA_TrackerJim, ricardo_MIA and 40 others
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