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ForumsMASH / Liver DiseaseMASH prevalence in GLP-1 users — November 2025 Page 6

MASH prevalence in GLP-1 users — November 2025

tampaLisa73 Sun, Mar 9, 2025 at 3:50 AM 44 replies 2,251 viewsPage 6 of 9
chris_chi24
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Mar 9, 2025 at 12:20 PM#26

Congrats tampaLisa73!! You should be so proud of yourself. 🎉

46 8nick_newbie, DadBodDave, AmyNC_wife and 43 others
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DebRD_ATL
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Mar 9, 2025 at 12:37 PM#27

Slightly tangential to MASH prevalence in GLP-1 but Admin reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

49 0RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 46 others
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maria_elpaso
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Mar 9, 2025 at 12:54 PM#28

Yep. My endo said the same thing about MASH prevalence in.

39 10TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 36 others
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GraceAZ_72
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Mar 9, 2025 at 1:11 PM#29

Reading this thread on MASH prevalence in GLP-1 hits close to home. Night shift nurse — I started at 283 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 58 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about MASH prevalence in — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Mar 9, 2025 at 5:11 PM
1 15JenPlateau
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KevinCompounds
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Mar 9, 2025 at 1:28 PM#30

As a pharmacist, I want to add some clinical context to this discussion on MASH prevalence in GLP-1 users November.

Building on what maria_elpaso said — the evidence base here is robust. The key publications to reference are from the FLOW program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
13 0NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 10 others
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