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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab ResultsPeople keep asking if I am sick and it is getting old Page 8

People keep asking if I am sick and it is getting old

ricardo_MIA Tue, Nov 18, 2025 at 8:15 AM 36 replies 1,472 viewsPage 8 of 8
jason_paloalto
Member
212
890
Nov 2024
Palo Alto, CA
Nov 18, 2025 at 7:35 PM#36

Relevant to People keep asking if I am — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 209 → 109 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

33 15tane_welly, Dr.PathRoch, mona_PHX and 30 others
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quinn_sf
Member
489
2,123
Jun 2024
San Francisco, CA
Nov 18, 2025 at 7:52 PM#37

Want to share my personal experience related to People keep asking if I am since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 265 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 60 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The People keep asking aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

11 20Dr.PathRoch, mona_PHX, andrew_nyc and 8 others
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Dr.PeteFamMed
Senior Member
2,012
9,234
Jan 2024
Minneapolis, MN
Nov 18, 2025 at 8:09 PM#38

Relevant to People keep asking if I am — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 211 → 111 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Nov 18, 2025 at 9:09 PM
44 16LindaRN_retired, tommy_boulder, hyun_seoul and 41 others
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DataDave
Senior Member
1,678
8,901
Apr 2024
Washington
Online
Nov 18, 2025 at 8:26 PM#39

Want to share my personal experience related to People keep asking if I am since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 282 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 67 lbs, my labs have normalized, and I am off 2 of my 3 medications. The People keep asking aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Last edited: Nov 18, 2025 at 9:26 PM
33 6amsterdam_pete, LondonLisa, mike_nyc and 30 others
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RegAffairsDC
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678
3,456
May 2024
Washington, DC
Nov 18, 2025 at 8:43 PM#40

jason_paloalto — that is really helpful context on People keep asking if I. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

Last edited: Nov 18, 2025 at 10:43 PM
3 11gary_naperville, sean_dublin, hannah_MT
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